Top 5 NFL Betting Picks for Thanksgiving Weekend

Top 5 NFL Betting Picks for Thanksgiving Weekend

From Lions vs Packers to Chiefs vs Cowboys, these picks offer value and insight based on recent performance and odds. Bet on home favorites and underdogs wisely.

NFLNovember 26, 2025Start Research
#1✓ Top Pick

Detroit Lions vs Green Bay Packers

Detroit Lions Moneyline

Expert Analysis

The Lions are favored at home against the Packers on Thanksgiving Day. Detroit's roster adjustments suggest a focus on strengthening their lineup, and the power rankings indicate a rising trend for the Lions. The odds of -142 offer a reasonable value for a home favorite on a holiday game.

American

-142

Decimal

1.70

@ FanDuel
#2✓ Top Pick

Kansas City Chiefs vs Dallas Cowboys

Kansas City Chiefs Moneyline

Expert Analysis

The Chiefs are heavily favored on the road against the Cowboys, reflecting their strong performance against the Colts as noted by Patrick Mahomes. The odds at -185, while steep, reflect the Chiefs' dominance and their ability to perform well away from home.

American

-185

Decimal

1.54

@ BetMGM
#3✓ Top Pick

Cincinnati Bengals vs Baltimore Ravens

Baltimore Ravens -7.5

Expert Analysis

The Ravens are significant favorites at home against the Bengals, with the power rankings indicating struggles for the Bengals. Betting on the Ravens to cover the 7.5-point spread at -110 odds is a solid choice given their strong home performance and the Bengals' recent form.

American

-110

Decimal

1.91

@ DraftKings
#4✓ Top Pick

Detroit Lions vs Green Bay Packers

Over 46.5 Points

Expert Analysis

Both the Lions and Packers have shown offensive capabilities this season, and Thanksgiving Day games often result in high-scoring affairs. The total of 46.5 points at -110 odds is appealing given the potential for both teams to contribute to a high-scoring game.

American

-110

Decimal

1.91

@ Caesars
#5✓ Top Pick

Kansas City Chiefs vs Dallas Cowboys

Dallas Cowboys +3.5

Expert Analysis

Despite being underdogs, the Cowboys have a chance to cover the +3.5 spread at home against the Chiefs. The Cowboys' rising status in the power rankings and the close nature of the spread at -110 odds make this an attractive bet for those looking for value.

American

-110

Decimal

1.91

@ BetRivers

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Updated 4 days ago Source: phillyvoice